甲苯咪唑及丙硫苯咪唑对大白鼠不同感染期的旋毛虫肌幼虫杀虫效力

试验采用甲苯咪唑、丙硫苯咪唑单独给药及联合给药,以300ppm混入饲料连续饲喂的方式,对105只人工感染旋毛虫的大白鼠,在不同感染期采用长短不同的给药时间。结果表明:不同感染期的旋毛虫肌幼虫以甲苯咪唑(150ppm)与丙硫苯咪唑(150ppm)联合给药疗效最佳,其次为甲苯咪唑。较经济的给药时间为:感染期在40～90天之间,横纹肌感染量为2343条/克,给药10天;感染期在90～165天之间,横纹肌感染量为2080条/克,给药15天,感染165天以上,横纹肌感染量为2080条/克,给药20天。

Effect of Mebendazole and Albendazole on Trichinella spiralis Muscle Larva

In the experiment, each of Mebendazole, Albendazole and mixture of them had been applied to feed 105 albino rats infected by Iricki-nella sprialis constantly by 300 ppm mixed with feed. At the different period, how long to apply medicine to the rats was not same. The experiment showed that the mixture of Mebendazole (150 ppm) and Albendazole (150 ppm) was the best to kill T. spiralis at the different infecting period. Next was Mebendazole. To kill muscle T. spiralis at the different infecting period, the time to apply drugs to the rats more economically was from 40 to 90 days after infecting through striped muscle by 2343 cysts per gram. The drugs had been applied for 10 days or from 90 to 165 days, 2080 cysts per gram. The drugs being applied for 15 days or more than 165 days,2080 cysts per gram, the drugs being applied for 20 days.