| miRNA调控鹿茸生长发育的研究进展 |
| |
| 作者姓名： | 韩若冰 韩磊 汤吉伟 赵德睿 李和平 |
| |
| 作者单位： | 东北林业大学野生动物与自然保护地学院 |
| |
| 基金项目： | 黑龙江省自然科学基金(C2017012)。 |
| |
| 摘 要： | 鹿茸是雄性鹿科动物(除驯鹿外)特有的能够周期性再生的器官,其生长发育受到多种因素的共同调控。miRNA(microRNA)是一类在真核生物中发现的内源性的具有调控功能的非编码RNA,在基因表达调控、细胞周期、生物体发育等方面发挥着重要的调控作用。本文从miRNA的相关技术、鹿茸组织中miRNA的鉴定、miRNA对生长因子的调控作用、miRNA对鹿茸细胞增殖的作用以及miRNA对鹿茸再生调控的研究几个方面就现有miRNA对鹿茸生长发育的研究进行总结和展望,为今后鹿茸生长发育机理的诠释具有一定的意义。
|
| 关 键 词： | MICRORNA 鹿茸 生长发育 软骨细胞 鹿茸再生 |
Review of miRNA Regulation of Growth and Development of Antler |
| |
| Authors: | HAN Ruobing HAN Lei TANG Jiwei ZHAO Derui LI Heping |
| |
| Institution: | (College of Wildlife and Protected Area,Northeast Forestry University,Harbin,150040,China) |
| |
| Abstract: | Antler can regenerate periodically and is unique to male deer(except reindeer).Its growth and development are controlled by many factors.miRNA(microRNA)is a kind of endogenous non-coding RNA with regulatory function found in eukaryotes.It is important in regulation of gene expression,cell cycles and biological development.In this paper,we review and summarize the research on miRNA related to antler growth and development.Our review perspectives included miRNA technology,identification of miRNA in antlers,regulation of miRNA on growth factors,regulation of miRNA on antler cell proliferation,and impact of miRNA on antler regeneration.Our objective was to further interpretation of the growth and development mechanisms of antlers. |
| |
| Keywords: | microRNA Antler Growth and development Cartilage Antler regeneration |
| 本文献已被 维普 等数据库收录！ |
|
