Piperidinyl amides with insecticidal activity from the maritime plant Otanthus maritimus |
| |
Authors: | Christodoulopoulou Lito Tsoukatou Maria Tziveleka Leto A Vagias Constantinos Petrakis Panos V Roussis Vassilios |
| |
Institution: | Department of Pharmacy, Division of Pharmacognosy and Chemistry of Natural Products, University of Athens, Panepistimiopolis Zografou, 15771 Athens, Greece. |
| |
Abstract: | Two new piperidine amides, N-(2E,4E,8Z)-tetradecatrienoyl]piperidine (1) and N-(2E,4E,8Z,11Z)-tetradecatetrenoyl]piperidine (2), along with the known metabolites N-(2E,4E)-tetradecadienoyl]piperidine (3), N-isobutyl-(2E,4E,)-tetradecadienamide (4), N-isobutyl-(2E,4E,8Z)-tetradecatrienamide (5), N-isobutyl-(2E,4E,8Z,11Z)-tetradecatetraenamide (6), sesamine (7), pinoresinol (8), and espeletone (9), were isolated from the dichloromethane/methanol extracts of the plant Otanthus maritimus Hoffman & Link collected from coastal areas in Greece. Pinoresinol (8) and espeletone (9) are reported for the first time as metabolites of O. maritimus. The structures of the new natural products were elucidated by interpretation of their NMR and high-resolution mass spectral measurements. The insecticidal properties of the crude extracts, essential oil, and isolated metabolites 1-9 were evaluated on Crematogaster scutellaris (Olivier) ants and Reticulitermes balkanensis (Clement) termites, showing significant levels of activity. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|