Evaluation of azathioprine on lesion severity and lymphocyte blastogenesis in dogs with perianal fistulas |
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Authors: | Harkin Kenneth R Phillips Dianne Wilkerson Melinda |
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Institution: | Department of Clinical Sciences, College of Veterinary Medicine, Kansas State University, Manhattan, Kansas 66506, USA. |
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Abstract: | Fourteen dogs with perianal fistulas were entered into a prospective clinical study to investigate the effects of long-term azathioprine on clinical outcome and to determine if the clinical results correlated with lymphocyte blastogenesis tests. Complete remission of perianal fistulas was seen in eight (57%) of 14 dogs; partial remission occurred in one (7%) dog; and no response was detected in five (36%) dogs. The results of lymphocyte blastogenesis assays did not correlate with therapeutic response. |
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