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Association of hyponatremia and hyperglycemia with outcome in dogs with congestive heart failure |
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| Authors: | Colleen A Brady DVM DACVECC Dez Hughes BVSc MRCVS DACVECC and Kenneth J Drobatz DVM MSCE DACVECC DACVIM |
| Institution: | From the Pacific Veterinary Specialists, 1980 41st Avenue, Capitola, CA 95010;, Department of Veterinary Clinical Sciences, The Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Herts AL9 7TA, UK;and Department of Clinical Studies, 3900 Delancey Street, Philadelphia, PA 19104-6010;. |
| Abstract: | Objective: To evaluate plasma sodium and glucose concentrations in dogs with congestive heart failure (CHF) prior to treatment and evaluate the differences between survivors and non‐survivors. Design: Retrospective study. Animals: Fifty‐nine dogs with CHF prior to receiving cardiac medication. Interventions: None. Measurements and main results: The mean plasma sodium concentration in dogs with CHF was below the reference range (144–156 mmol/L) and significantly lower (P=0.009) in non‐survivors (141±6 mmol/L) compared with survivors (147±4 mmol/L). The mean plasma glucose concentration was above the reference range (76–117 mg/dL) and significantly higher (P=0.004) in non‐survivors (128±52 mg/dL) compared with survivors (100±13 mg/dL). Forty‐four percent of non‐survivors had concurrent low plasma sodium and high plasma glucose concentrations, whereas no survivors had both abnormalities (P<0.0001). Conclusions: Lower plasma sodium and higher plasma glucose are associated with a worse outcome in dogs with CHF. |
| Keywords: | canine chronic valvular disease dilated cardiomyopathy plasma glucose plasma sodium |