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Haemophilia A in the cocker spaniel: a case report
Authors:R DPearce  M L Cooper  
Institution:*Department of Clinical Studies, University of Guelph, Guelph, Ontario, NIG 2WI Canada;†Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, Ontario, NIG 2WI Canada
Abstract:A four-year-old entire male cocker spaniel was presented with a history of dyspnoea due to tracheal stenosis. As part of the clinical approach, a coagulation screening profile revealed moderately reduced levels of Factor VIII procoagulant activity (VIII: C), but elevated factor VHI-related antigen levels (VIIIR: Ag). A diagnosis of haemophilia A (classic haemophilia) was made and the tracheal stenosis attributed to a mediastinal haematoma. The dyspnoea was alleviated by the surgical insertion of a tracheostomy tube and the dog was treated with citrated whole blood and fresh-frozen canine plasma. Response to treatment was excellent and follow-up radiography three months later revealed resolution of the tracheal stenosis.
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