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| 羊肚菌水提物对急性肝损伤的干预作用 | |
| 引用本文： | 周丽伟,陈彦,孙玉军. 羊肚菌水提物对急性肝损伤的干预作用[J]. 中国食用菌, 2006, 25(6): 36-37 |
| 作者姓名： | 周丽伟 陈彦 孙玉军 |
| 作者单位： | 1. 安徽大学生命科学学院,安徽省中药研究与开发重点实验室,安徽,合肥,230039 2. 安徽大学生命科学学院,安徽省中药研究与开发重点实验室,安徽,合肥,230039;安徽科技学院生命科学学院,安徽,凤阳,233100 |
| 基金项目： | 安徽省教育厅自然科学基金;安徽大学校科研和教改项目 |
| 摘 要： | 研究羊肚菌水提物对CCl4致小鼠急性肝损伤的保护作用。预防给药16d后．采用CCl4复制小鼠急性肝损伤模型，24h后。眼眶取血．测定血清中丙氨酸氨基转移酶（ALT）、超氧化物歧化酶（SOD）、丙二醛（MDA）以及血清蛋白的变化．观察羊肚菌水提物对急性肝损伤的保护作用。羊肚菌水提物能明显降低模型组的血清转氨酶、肝脂质过氧化物含量抑制蛋白流失及肝脏肿大．说明羊肚菌水提物对小鼠肝脏的化学损伤有显著的保护作用． |
| 关 键 词： | 羊肚菌 急性肝损伤 |
| 文章编号： | 1003-(8310)2006(06)-0036-02 |
| 收稿时间： | 2006-10-05 |
| 修稿时间： | 2006-10-05 |
Protective Effects of Morchella esculenta on Acute Hepatic Injury Induced by CCl4 in mice |
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| ZHOU Li-wei,CHEN Yan,SUN Yu-jun. Protective Effects of Morchella esculenta on Acute Hepatic Injury Induced by CCl4 in mice[J]. Edible Fungi of China, 2006, 25(6): 36-37 | |
| Authors: | ZHOU Li-wei CHEN Yan SUN Yu-jun |
| Affiliation: | 1.School of life science, Anhui Unive~ity, Hefei 230039, China; The key lab of Chinese traditional medicine research and development of Anhui Province, Hefei 230039, China; 2. School of Life Science, Anhui Science and Technology University, Fengyang 233100, China |
| Abstract: | To study the protective effects of Morchella esculenta on acute hepatic injury induced by CCl_4 in miee.Pretreated with the extract from Morchella esculenta for 16 days,mice modles of acute hepatic injury were estabhshed by the treatment of carbon tetrachloride(CCl_4) .After 24 hours,the protective effects of the extract from Morchella esctdenta in acute hepatic injury were observed through determing the activities of alanine aminotransferase(ALT),(SOD),Maleie Dialdehyde(MDA),and the contents of proteins in serum. The extract from Morchella eseulenta significantly reduce the level of serum ALT,MDA and the hepatic index,and increasing SOD activity,level of serum protein.It has showed that Morehella esctdenta has proactive effects on mice acute hepatic injury. |
| Keywords: | CCl4 |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |