| 2-氰基-3- 氨基-3-脂肪氨基丙烯酸乙酯的合成 |
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| 引用本文： | 余申义,李正名.2-氰基-3- 氨基-3-脂肪氨基丙烯酸乙酯的合成[J].农药学学报,2002,4(3):79-82. |
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| 作者姓名： | 余申义 李正名 |
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| 作者单位： | 1.北京化工大学 理学院,北京 100029 |
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| 摘 要： | 以3-氨甲基吡啶和2-氯-5-氨甲基吡啶为原料先与2-氰基-3,3-二甲硫基丙烯酸乙酯反应得到中间体 2a和2b, 不经分离,直接与脂肪胺反应,合成了7个未见文献报道的开环类吡虫啉结构化合物 3 。所有目标化合物(包括 2a和2b )均经元素分析和1H NMR确证,并对其构型进行了讨论。
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| 关 键 词： | 3-氨甲基吡啶 烯酮二硫缩醛 脂肪胺 合成 生物活性 |
| 文章编号： | 1008-7303(2002)03-0079-04 |
Synthesis of 2-Cyano-3- -3-Aliphatic Amine Ethyl Acrylate |
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| YU Shen-yi and LI Zheng-ming.Synthesis of 2-Cyano-3- -3-Aliphatic Amine Ethyl Acrylate[J].Chinese Journal of Pesticide Science,2002,4(3):79-82. |
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| Authors: | YU Shen-yi and LI Zheng-ming |
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| Institution: | 1.Institute of Science, Beijing University of Chemical Technology, Beijing 100029,China2.Research Institute of Elemento-organic Chemistry, Nankai University,Tianjin 300071,China |
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| Abstract: | After 3 aminomethyl or 2 chloride 5 aminomethyl pyridine reacted with 2 cyano 3,3 dimethylthio ethyl acrylate the simple fatty amines were added to the reactant. The intermediates were not separated to yield seven novel compounds. All the structures of new compounds were confirmed by elemental analysis and H 1 NMR. The configurations of the compounds were discussed in contrast with the 1H NMR of the intermediates. |
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| Keywords: | aminomethylpyridine ketene dithioacetals fatty amine synthesis biologic activity |
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