Postovulatory Effect of Intravenous Administration of Lipopolysaccharide (Escherichia coli, O55:B5) on the Endocrine Status of Recently Ovulated Sows |
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| Authors: | AM Mwanza A Madej H Kindahl N Lundeheim & S Einarsson |
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| Institution: | Department of Obstetrics and Gynaecology, Swedish University of Agricultural Sciences, Centre for Reproductive Biology in Uppsala (CRU), Uppsala, Sweden;Department of Animal Physiology, Swedish University of Agricultural Sciences, Centre for Reproductive Biology in Uppsala (CRU), Uppsala, Sweden;Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Centre for Reproductive Biology in Uppsala (CRU), Uppsala, Sweden |
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| Abstract: | The effects of lipopolysaccharide ( Escherichia coli , O55:B5), administered 18 h after ovulation in the second oestrus after weaning on the hormonal profiles in 14 Swedish cross-bred (Landrace × Yorkshire) multiparous sows were studied. The endotoxin group (E-group) sows were administered with 300 ng/kg of lipopolysaccharide (LPS) whereas the control group (C-group) sows were administered 5 ml of saline intravenously via an indwelling jugular cannula. Blood samples for hormonal analyses were collected from all sows until slaughter. In the E-group, progesterone, cortisol and prostaglandin F2α metabolite levels increased significantly (p < 0.05) following LPS compared with the C-group. It can be concluded from this study that apart from elevating cortisol and prostaglandin F2α metabolite, LPS also elevates progesterone levels. |
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