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| 线粒体调控细胞凋亡的研究进展 | |
| 引用本文： | 吴兰芳,杨爱珍,刘和,王有年.线粒体调控细胞凋亡的研究进展[J].中国农学通报,2010,26(8):63-68. |
| 作者姓名： | 吴兰芳 杨爱珍 刘和 王有年 |
| 作者单位： | 1. 农业部都市农业(北方)重点开放实验室,北京,102206;山西农业大学园艺学院,山西,太谷,030801 2. 北京农学院生物技术系,北京,102206 3. 山西农业大学园艺学院,山西,太谷,030801 4. 农业部都市农业(北方)重点开放实验室,北京,102206 |
| 基金项目： | 北京市自然科学基金重点项目，北京市自然科学基金项目，北京市科委区县专项资金项目，北京市教委平台建设项目，北京市教委都市农业学科群建设项目，北京市属高校人才强教深化计划资助项目 |
| 摘 要： | 线粒体与细胞凋亡有着密切的关系。细胞凋亡过程中线粒体释放膜间隙中与凋亡相关的活性物质,如细胞色素C、A IF、Smac/D IABLO等, 促进活性氧的产生，线粒体上MPTP孔道的开放,削弱了线粒体膜两侧的质子梯度,导致ATP合成下降;释放的活性物质激活Caspase,引起细胞凋亡。 |
| 关 键 词： | 烤烟 烤烟 砂培基质 浅水育苗 漂浮育苗 |
| 收稿时间： | 2009-11-17 |
| 修稿时间： | 2009-12-01 |
The Study Progress of apoptosis of Regulation of mitochondrial |
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| Wu Lanfang,Yang Aizhen,Liu He,WangYounian.The Study Progress of apoptosis of Regulation of mitochondrial[J].Chinese Agricultural Science Bulletin,2010,26(8):63-68. | |
| Authors: | Wu Lanfang Yang Aizhen Liu He WangYounian |
| Institution: | 1Key Laboratory of Urban Agriculture (North) of Ministry of Agriculture P.R. China, Beijing 102206; 2Department of Biotechnology of Beijing University of Agriculture, Beijng 102206; 3College of Horticulture Shanxi Agriculture University, Taigu Shanxi 030801 |
| Abstract: | Mitochondrion has close relationship with apoptosis. Some active substances, such as Cytochrome C, A IF, Smac /D IABLO are released from mitochondrion, intermembrane space and the MPTP channel of mitochondrion is opened. And promote the generation of reactive oxygen species.Then the electrochemical proton gradient between the outside and the inside membrane of mitochondrion is weakened,which results in decline of the synthesis of ATP and active substances mentioned above active caspase. So apoptosis is induced. |
| Keywords: | apoptosiszz |
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