Antiviral Activity of Carrageenans and Processing Implications |
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| Authors: | Milena lvarez-Vias Sandra Souto Noelia Flrez-Fernndez Maria Dolores Torres Isabel Bandín Herminia Domínguez |
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| Institution: | 1.CINBIO, Faculty of Science, Universidade de Vigo, Campus Ourense, As Lagoas, 32004 Ourense, Spain; (M.Á.-V.); (N.F.-F.); (M.D.T.);2.Departamento de Microbioloxía e Parasitoloxía, Instituto de Acuicultura, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain; (S.S.); (I.B.) |
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| Abstract: | Carrageenan and carrageenan oligosaccharides are red seaweed sulfated carbohydrates with well-known antiviral properties, mainly through the blocking of the viral attachment stage. They also exhibit other interesting biological properties and can be used to prepare different drug delivery systems for controlled administration. The most active forms are λ-, ι-, and κ-carrageenans, the degree and sulfation position being determined in their properties. They can be obtained from sustainable worldwide available resources and the influence of manufacturing on composition, structure, and antiviral properties should be considered. This review presents a survey of the antiviral properties of carrageenan in relation to the processing conditions, particularly those assisted by intensification technologies during the extraction stage, and discusses the possibility of further chemical modifications. |
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| Keywords: | sulfated polysaccharides red seaweed extraction depolymerization |
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