Effect of Synthetic Lysine Vasopressin on Adrenocortical Secretion

By means of direct arterial perfusion of the adrenal glands in the dog it has been shown that synthetic lysine vasopressin stimulates the secretion of hydrocortisone. This effect is not mediated via the adenohypophysis or any other organ but is rather the result of direct stimulation of the adrenal cortex by vasopressin itself.