| 哺乳类动物胃肠道内味觉受体的信号研究 |
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| 引用本文： | 陈晓慧,张春雷,陈宏,房兴堂.哺乳类动物胃肠道内味觉受体的信号研究[J].中国牛业科学,2012,38(5):49-52. |
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| 作者姓名： | 陈晓慧 张春雷 陈宏 房兴堂 |
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| 作者单位： | 1. 江苏师范大学细胞与分子生物学研究所,江苏徐州,221116
2. 江苏师范大学细胞与分子生物学研究所,江苏徐州221116 西北农林科技大学动物科技学院／陕西省农业分子生物学重点实验室,陕西杨凌712100 |
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| 基金项目： | 国家自然科学基金，江苏省自然科学基金，国家现代肉牛牦牛产业技术体系专项 |
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| 摘 要： | 胃肠道内容物的分子识别对食物的消化、摄取量的控制、胰岛素的分泌、新陈代谢等起到重要作用。这些过程很有可能受到激素/中枢神经通路的介导。但是,有关于胃肠道的味觉识别机制还不清楚。本文综述了最新的研究结果,表明了舌上皮组织的特异性味觉受体细胞的化学感应机制在内分泌细胞中也发挥作用,用来感知肠腔内容物的化学组成。
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| 关 键 词： | 味觉受体 胃肠道内分泌细胞 化学感应 |
Research on Taste Receptor Signaling in Mammalian Gut |
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| CHEN Xiao-hui,ZHANG Chun-lei,CHEN Hong,FANG Xing-tang.Research on Taste Receptor Signaling in Mammalian Gut[J].China Cattle Science,2012,38(5):49-52. |
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| Authors: | CHEN Xiao-hui ZHANG Chun-lei CHEN Hong FANG Xing-tang |
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| Institution: | 1. Institute of Cellular and Molecular Biology ,School of Life Science , J iangsu Normal University , Xuzhou J iangsu 22111612. College of Animal Science and Technology, Northwest A F University ,Shaanxi Key Laboratory of AgriculturalMolecular Biology, Yangling , Shaancci 712100) |
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| Abstract: | Molecular sensing by gastrointestinal（GI） cells plays a crucial role in the control of multiple fundamental functions including digestion, regulation of caloric intake, pancreatic insulin secretion, and metabolism. These processes are likely to be mediated by initiation of humoral and/or neural pathways. However, the gastrointestinal sense of taste recognition events and mechanism（s） involved are still un- known. This article reviews the current evidences that the chemosensory machinery discovered in special- ized taste receptor cells of lingual epithelium is operational in enteroendocrine cells to sense the chemical composition of luminal contents of gut. |
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| Keywords: | taste receptor gastrointestinal endocrine cells chemosensory |
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