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Induction in vitro of microtubular crystals by vinca alkaloids |
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| Authors: | K G Bensch R Marantz H Wisniewski M Shelanski |
| Abstract: | The addition of vinblastine or vincristine to solutions of pure microtubule protein or to supernatants from high-speed centrifugation of rabbit-brain homogenates results in the formation of a fine precipitate. Examination of this precipitate by electron microscopy reveals ordered structures with areas of ladder-like configuration. |
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