Goats are susceptible to Bubaline alphaherpesvirus 1 infection: Results of an experimental study |
| |
| Affiliation: | 1. Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, 1600 S. 16th Street, Ames, IA 50011, USA;2. Laboratório de Pesquisa em Virologia Animal, Departamento de Medicina Veterinária Preventiva, Universidade Federal de Minas Gerais, Belo Horizonte, MG 31270-901, Brazil;3. Department of Diagnostic Medicine and Pathobiology, Kansas State University, Manhattan, KS 66506, USA;4. Department of Biomedical Sciences and Pathobiology, Center for Molecular Medicine and Infectious Diseases, College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA;5. Institute of Preventive Veterinary Medicine & Key Laboratory of Animal Virology of Ministry of Agriculture, College of Animal Sciences, Zhejiang University, Hangzhou, 310058, China;6. The Roslin Institute and The Royal (Dick) School of Veterinary Studies, University of Edinburgh, Midlothian EH25 9RG, UK |
| |
| Abstract: | Herpesvirus infections are generally subjected to strong host species restriction, although virological and serological investigations have revealed the possibility of cross-species infections in closely related animal species. In this study we evaluated susceptibility of goats to infection by Bubaline alphaherpesvirus 1 (BuHV-1). Four goats were inoculated intra-nasally with BuHV-1 and monitored clinically, virologically and serologically for 42 days. None of the goats displayed clinical signs although all the animals variably shed the virus by the nasal route during the first 12 days after infection. BuHV-1 was also detected in the white blood cells of two animals in the first week post infection. The results suggest that goats are susceptible to BuHV-1 infection and that they could play an epidemiological role in the circulation/transmission of the virus among domestic and wild ruminants and impact to some extent on the control plans for herpesviruses in cattle. |
| |
| Keywords: | Bubaline alphaherpesvirus 1 Epidemiology Experimental infection Goats Susceptibility PCR |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
