The effect of "Ferrodex", vitamin A and "Rovimix beta-carotene" on the iron and copper levels in blood plasma of calves

The effect of Ferrodex, vitamin A and synthetic beta-carotene on the content of iron and copper in the blood serum has been investigated in three groups of calves: I control group without vitamin supplements, II group received only once with the first colostrum dose 1.5 million IU of vitamin A, III group received Rovimix beta carotene containing 10 per cent of the synthetic beta carotene with Mlekomix from the 21st day to the 13th week of life. Moreover half of the calves from each group received Ferrodex intramusculary. Content of iron, total iron binding capacity by serum proteins, level of indirect and direct copper as well as the content of ceruloplasmin were determined in the blood serum of calves. Moreover hematocrit and hemoglobin content in the blood were determined. The results obtained show that a triple intramuscular injection of Ferrodex caused an increase of the level of iron, copper and ceruloplasmin in the blood serum of calves. However, a single administration of vitamin A to the calves or a continuous administration of Rovimix beta-carotene decreased significantly the level of iron and ceruloplasmin copper in blood serum as well as caused a more dynamic ceruloplasmin synthesis with a simultaneous increase in its utilization.