钙蛋白酶抑制蛋白对猪肉肉质的影响

钙蛋白酶系统主要由钙蛋白酶(u2-calpain,CAPN1;m2-calpain,CAPN2)及钙蛋白酶抑制蛋白(calpastatin)组成,calpain是存在于细胞质中的依赖于Ca2+的钙中性蛋白酶,蛋白酶系统是主要的蛋白质降解物。calpastatin是钙蛋白酶的内源性抑制蛋白。研究表明,Calpastatin在肌原纤维蛋白降解中起着重要作用。因此,对肌肉生长和嫩度有重要影响。本文综述了钙蛋白酶抑制蛋白的结构组成,对肉嫩度影响的机理和钙蛋白酶抑制蛋白基因的定位。

The Affection of Calpastatin to Meat Quality

Calpain system consists of u-calpain,m-calpain,the calcium-dependent neutral proteases,and their endogenous inhibitor,calpastatin.Calpain system is probably the major proteolytic in protein degradation,Calpastatin(CAST)is the endogenous inhibitor of calpain system,which plays an important role in myofibrillar protein degradation.The muscle growth and postmortem tenderization of meat are highly related to the degree of Calpastatin,so the activity of Calpastatin has an important effect on muscle growth and meat tenderness.This paper reviews the structure,function and regulation of Calpastatin and the relationship between Calpastatin and meat tenderness and gene orientation.