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Molecular order of participation of inhibitors (or activators) in biological systems
Authors:R B Loftfield  E A Eigner
Abstract:
From a Hill plot it is frequently possible to determine whether exactly one, two, or several inhibitor (or activator) molecules are involved in a critical rate-determining biological process.
Keywords:
引证文献(本文共被引4次):
[1]、R B Loftfield, E A Eigner, A Pastuszyn, T N Lövgren, and H Jakubowski.Conformational changes during enzyme catalysis: role of water in the transition state.[J].Proceedings of the National Academy of Sciences of the United States of America,1980,77(6):3374-3378.
[2]、K K Kalghatgi and P V Subba Rao.Microbial L-phenylalanine ammonia-lyase. Purification, subunit structure and kinetic properties of the enzyme from Rhizoctonia solani.[J].The Biochemical journal,1975,149(1):65-72.
[3]、Sidney Pestka.Peptidyl-Puromycin Synthesis on Polyribosomes from Escherichia coli[J].Proceedings of the National Academy of Sciences of the United States of America,1972,69(3):624-628.
[4]、L. M. S. Chang and F. J. Bollum.Deoxynucleotide-Polymerizing Enzymes of Calf Thymus Gland, IV. Inhibition of Terminal Deoxynucleotidyl Transferase by Metal Ligands[J].Proceedings of the National Academy of Sciences of the United States of America,1970,65(4):1041-1048.
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