Correlations among <Emphasis Type="Italic">Anaplasma marginale</Emphasis> parasitemia and markers of oxidative stress in crossbred calves |
| |
Authors: | Ujjwal Kumar De Sahadeb Dey Partha Sarathi Banerjee Monalisa Sahoo |
| |
Institution: | (1) Division of Medicine, Indian Veterinary Research Institute, Izatnagar, 243122, Uttar Pradesh, India;(2) Division of Parasitology, Indian Veterinary Research Institute, Izatnagar, 243122, Uttar Pradesh, India;(3) Division of Pathology, Indian Veterinary Research Institute, Izatnagar, 243122, Uttar Pradesh, India; |
| |
Abstract: | The present study was designed to determine the correlations among Anaplasma marginale parasitemia and markers of oxidative stress in crossbred calves. Blood was collected from 11 crossbred calves infected with
A. marginale along with 11 healthy crossbred calves as controls for determination of hematology and oxidative stress indicators. Percentage
of parasitemia in infected calves varied from 0.8% to 6.0%. The values of hematological indicators and antioxidant enzymes
were decreased, whereas erythrocytic lipid peroxidation (LPO) and plasma nitrate (NO) level were significantly (p < 0.05) augmented in A. marginale-infected animals over healthy group. Parasitemia was positively correlated (p < 0.01) with erythrocytic LPO and plasma NO and negatively correlated (p < 0.01) with hematological indicators and antioxidant enzymes. In addition, erythrocytic LPO was negatively correlated (p < 0.01) with the hemoglobin, erythrocyte count, and packed cell volume. From the present study, it can be concluded that
anaplasmosis in crossbred calves is associated with a parasitic load-dependent oxidative damage as indicated by poor antioxidant
status and enhanced oxidative stress, which are contributed to severe anemia. |
| |
Keywords: | |
本文献已被 PubMed SpringerLink 等数据库收录! |
|