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The high prevalence of hepatitis E virus infection in wild boars in Ibaraki Prefecture,Japan
Authors:Takumi MOTOYA  Noriko NAGATA  Harumi KOMORI  Ikuko DOI  Miho KUROSAWA  Toshimasa KETA  Nobuya SASAKI  Koji ISHII
Affiliation:1)Ibaraki Prefectural Institute of Public Health, 993–2 Kasahara-cho, Mito, Ibaraki 310–0852, Japan;2)Laboratory of Laboratory Animal Science and Medicine, Faculty of Veterinary Medicine, Kitasato University, Higashi 23–35–1, Towada, Aomori 034–8628, Japan;3)Department of Virology II, National Institute of Infectious Diseases, 4–7–1 Gakuen, Musashimurayama, Tokyo 208–0011, Japan
Abstract:Hepatitis E virus (HEV) is known as a causative agent of zoonosis and food poisoning.Pigs and some species of wild animals, including wild boar, are known to be a reservoir ofHEV. In this study, we investigated the situation regarding HEV infection in wild boars inIbaraki Prefecture, Japan. Serum, liver and feces samples from 68 animals were collected,and the presence or absence of HEV genomic RNA and HEV antibodies were analyzed. The viralgenome was detected in samples from 7 (10.3%) animals, with all HEVs classified asgenotype 3, subtype 3b. HEV antibodies were detected in samples from 28 (41%) animals.This report demonstrates for the first time the high prevalence of HEV infection in wildboars in Ibaraki Prefecture.
Keywords:ELISA   genotype   hepatitis E virus   phylogenetic analysis   wild boar
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