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CASE REPORT AND CLINICAL REVIEW: Acute lameness associated with osseous metastasis of a peri-renal carcinoma in a horse
Authors:AC Young  KL Hoffmann  AP Begg  DA Major
Institution:1. University of Sydney, Diagnostic Imaging, Faculty of Veterinary Science, University of Sydney, Sydney, NSW, Australia;2. Symbion Vetnostics, North Ryde, NSW, Australia;3. Agnes Banks Equine Clinic, Agnes Banks, NSW, Australia
Abstract:We present a case of aggressive metastatic carcinoma in a horse that was initially presented for shoulder lameness. Although radiography and scintigraphy were useful for localising a lesion in the proximal humerus, subsequent development of non-specific signs of systemic disease prompted further evaluation. Haematology and blood biochemistry, urinalysis and ultrasonography were all instrumental in identifying renal involvement. A diagnosis of a peri-renal mass causing secondary renal failure prompted euthanasia of the horse because of the poor prognosis. Antemortem findings were supported by necropsy, with secondary lesions also identified in the spleen, liver, 8th left rib and proximal humerus. Histological examination yielded a diagnosis of undifferentiated metastatic carcinoma.
Keywords:carcinoma  horses  lameness  metastasis  peri-renal mass  scintigraphy
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