Erythrocyte Osmotic Fragility and Hematological Responses of Horses Administered Ascorbic Acid and Exposed to Road Transportation |
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| Institution: | 1. Department of Veterinary Physiology, Ahmadu Bello University, Zaria, Nigeria;2. Department of Veterinary Medicine, Ahmadu Bello University, Zaria, Nigeria;1. Department of Veterinary Medical Sciences, University of Bologna, Ozzano Emilia, Bologna, Italy;2. AUB-INFA, University of Bologna, Granarolo dell’Emilia, Bologna, Italy;3. Department of Large Animal Clinical Sciences, College of Veterinary Medicine, Texas A&M University, College Station, TX;1. Université Paris-Est, Ecole Nationale Vétérinaire d''Alfort, CIRALE-Hippolia, Goustranville, France;2. INRA, USC BPLC 957, Maisons-Alfort, France;3. Université Paris-Est, Ecole Nationale Vétérinaire d''Alfort, Maisons-Alfort, France;4. OTR3, Paris, France;1. Department of Pathophysiology, Faculty of Veterinary Medicine, University of Life Sciences, Lublin, Poland;2. Department and Clinic of Animal Reproduction, Sub-Department of Andrology and Biotechnology of Animal Reproduction, Faculty of Veterinary Medicine, University of Life Sciences, Lublin, Poland;1. Centro de Investigación en Encefalopatías y Enfermedades Transmisibles Emergentes, Departamento de Patología Animal, Facultad de Veterinaria, Universidad de Zaragoza, Zaragoza, Spain;2. Unidad de Microbiología e Inmunología, Departamento de Patología Animal, Facultad de Veterinaria, Universidad de Zaragoza, Zaragoza, Spain;3. Departamento de Anatomía, Embriología y Genética Animal, Laboratorio de Genética Bioquímica (LAGENBIO), Facultad de Veterinaria, Universidad de Zaragoza, Zaragoza, Spain;4. Departamento de Patología Animal, Hospital Veterinario, Facultad de Veterinaria, Universidad de Zaragoza, Zaragoza, Spain;1. Department of Animal Science, College of Agriculture and Natural Resources, University of Tehran, Karaj, Iran;2. Department of Animal Production, Faculty of Agriculture, Suez Canal University, Ismailia, Egypt;1. Cuerpo Académico de Zoonosis y Enfermedades Emergentes, Facultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma de Nuevo León, Escobedo, Nuevo León, México;2. Epidemiología Veterinaria, Facultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma de Nuevo León, Escobedo, Nuevo León, México;3. Department of Pathology and Microbiology, Atlantic Veterinary College, University of Prince Edward Island, Charlottetown, Canada |
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| Abstract: | The experiment was performed to evaluate the ameliorative effect of ascorbic acid (AA) on some hematological parameters and erythrocyte osmotic fragility (EOF) in horses transported by road. A total of 14 horses, consisting of seven experimental and seven control horses, were used for the experiment. Before the transportation, blood samples were obtained by jugular venipuncture from all the horses. Experimental horses were administered with AA (200 mg/kg dissolved in 20 mL of distilled water per os), whereas the control horses were given 20 mL of distilled water per os. Thereafter, the animals were transported for 6 hours and blood samples collected after transportation. Packed cell volume and hemoglobin concentration were higher (P < .05) in experimental than the control group, whereas total leukocytes reduced significantly (P < .05) in experimental in comparison with the control horses. Lymphocyte, neutrophil counts, neutrophil/lymphocyte ratio, and total protein decreased in experimental horses in comparison with control, but they were not significant (P > .05). Erythrocyte osmotic fragility was lower in experimental than the control at 0.3% NaCl concentration (P < .05). The result of the present study revealed that AA ameliorated changes in hematological parameters and EOF induced by road transport stress, partly because of its antioxidant properties. |
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| Keywords: | Horse Transport Ascorbic acid Hematological parameter Erythrocyte osmotic fragility |
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