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阿米卡星与替米考星对奶牛乳房炎常见病原菌的联合药敏试验
引用本文:孙雪峰,李引乾,张国士,薛琴,荆娜娜.阿米卡星与替米考星对奶牛乳房炎常见病原菌的联合药敏试验[J].安徽农业科学,2006,34(23):6201-6202.
作者姓名:孙雪峰  李引乾  张国士  薛琴  荆娜娜
作者单位:西北农林科技大学动物科技学院,陕西杨凌,712100;西北农林科技大学动物科技学院,陕西杨凌,712100;西北农林科技大学动物科技学院,陕西杨凌,712100;西北农林科技大学动物科技学院,陕西杨凌,712100;西北农林科技大学动物科技学院,陕西杨凌,712100
摘    要:研究了阿米卡星和替米考星2种药物在无乳链球菌、停乳链球菌、金黄色葡萄球菌、致病性大肠埃希菌4种奶牛乳房炎常见病原菌联合药敏试验中的相互作用,结果表明,阿米卡星与替米考星对各菌的MIC均在7.81~62.50μg/ml之间;二者联合后的FIC指数范围0.75~1.0;二者联合用药时为相加作用。

关 键 词:阿米卡星  替米考星  奶牛乳房炎  联合药敏试验
文章编号:0517-6611(2006)23-6201-02
收稿时间:07 12 2006 12:00AM
修稿时间:2006-07-12

Susceptibility Testing of the Combination of Amikacin and Tilmicosin against Some Pathogenic Bacteria of Dairy Cow Mastitis
SUN Xue-feng et al.Susceptibility Testing of the Combination of Amikacin and Tilmicosin against Some Pathogenic Bacteria of Dairy Cow Mastitis[J].Journal of Anhui Agricultural Sciences,2006,34(23):6201-6202.
Authors:SUN Xue-feng
Abstract:To study the interaction between Amikacin and Tilmicosin against the bacteria of dairy cow mastitis,the susceptibility testing of drug combination to Streptococcus agalactiae,Streptococcus dysgalactiae,Staphylococcus aureus and E.coli in vitro was done.The minimal inhibitory concentration(MIC) of Amikacin and Tilmicosin against the batertia was determined with the grade dilution method.The fractional inhibitory concentration(FIC) was measured with checkerboard microdilution method.The results showed MIC of Amikacin and Tilmicosin against the batertia was 7.81~62.50 μg/mL and the FIC of Amikacin combined with Tilmicosin was 0.75~1.0.The study suggested that the combination of Amikacin and Tilmicosin to the bacteria had additive effect.
Keywords:Amikacin  Tilmicosin  Dairy cow mastitis  Combination susceptibility testing
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