Affiliation: | Institute of Tropical Veterinary Medicine and Department of Veterinary Microbiology and Parasitology, College of Veterinary Medicine, Texas A&M University, College Station, TX 77843, U.S.A. The Laboratory Animal Research Center, The Rockefeller University, 1230 York Ave, New York, NY 10021, U.S.A. |
Abstract: | A review of the recent and/or significant literature concerning Corynebacterium equi, including its morphologic, biochemical, immunological, and pathological characteristics in the foal, humans and other animals is presented. The similarity in the tissue responses of mammalian hosts to C. equi and Mycobacterium spp. is discussed.The antigenic structure and virulence factors associated with C. equi. other corynebacteria and mycobacteria are compared. The immunological aspects of resistance to C. equi are considered. The evidence suggests that the major immune response elicited in the foal by C. equi is cell-mediated. However, the immunopathogenic mechanism needs clarification. Areas of future research are suggested. |