牛IGF-1基因及其单核苷酸多态性与产奶性状关系的研究进展

产奶性状是奶牛生产中的重要经济性状，由微效多基因决定。影响奶牛产奶性状的基因较多，胰岛素样生长因子-1（insulin-like growth factor-1，IGF-1）基因作为影响奶牛产奶性状的一个候选基因，它的突变可导致其结构和功能发生改变，以及由此引起的产奶性状发生变化。作者就IGF-1的结构与功能及其基因单核苷酸多态性（single nucleotide polymorphisms，SNPs）与产奶性状的相关研究进展进行了综述，旨在为进行奶牛产奶性状的相关研究提供理论参考。

Research Progress on Bovine IGF-1 Gene and Association of its SNPs with Milk Production Traits

Milk production traits were the important economic traits in the cow production，and were determined by many genes with little effect.Insulin-like growth factor-1 （IGF-1） gene as one of many candidate genes for milk production traits，the mutation of IGF-1 gene might result in the change of IGF-1 structure，and the change in milk production traits.The author reviewed the structure and function of IGF-1 gene and research progress on its single nucleotide polymorphisms and association with milk production traits in bovine，aiming to provide a theoretical reference for relevant studies on milk production traits.