GABAergic神经元在BARREL和VPM区组织结构及形态特点的免疫组织化学研究

目的]研究GABAergic神经元在VPM和"barrel"区的组织结构及形态特点;方法]通过免疫组织化学的方法和激光共聚焦电子显微镜研究GABAergic神经元在VPM和"barrel"区分布状态;结果]GABAergic神经元在VPM和"barrel"区分布状态不同,信息传递这2个区域编码程度也不一样;GABAergic在VPM区主要分布在列与列之间,且呈非对称分布,而GABAergic神经元的胞体、树突和轴突出现限定在"barrel"内,与周围"barrel"很少形成突触联系。结论]提示VPM和"barrel"可能在信息传递及处理过程中具有不同的功能。

The Topography and Organization of GABAergic neurons in the VPM and Barrel By Immunohistochemitry

Objective] Study on the structure of GABAergic neurons in the VPM and "barrel".Method]The distribution of GABAergic neurons in the two areas were studied through immunohistochemistry and Laser Scanning Confocal Microscope.Result]The results show that the distribution of GABAergic neurons in VPM and barrel are different,and the coding of information transmission in the two areas are also dissimilar,GABAergic neurons mainly distribute among the lines asymmetrically in VPM,the somata,dendrite and axon of GABAergic neurons are restricted in the "barrel",rarely having synaptic connections with other "barrel"around.Conclusion]VPM and barrel may have different roles in transmission and on processing of information.