| 绵羊肺炎支原体 p113 基因的序列分析及功能预测 |
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| 引用本文： | 杨发龙,张焕容,汤 承,岳 华.绵羊肺炎支原体 p113 基因的序列分析及功能预测[J].华南农业大学学报,2013,34(1):117-121. |
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| 作者姓名： | 杨发龙 张焕容 汤 承 岳 华 |
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| 作者单位： | 西南民族大学 生命科学与技术学院;西南民族大学 生命科学与技术学院;西南民族大学 生命科学与技术学院;西南民族大学 生命科学与技术学院 |
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| 基金项目： | 中央高校基本科研业务费专项资金(11NZYQN34); 山羊现代产业链关键技术集成研究与产业化示范(2011NZ0003) |
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| 摘 要： | 采用多种软件对p113基因的相似性、跨膜结构、重复序列、信号肽、抗原表位等进行预测,并与同源序列进行比较分析.结果表明,p113基因是猪肺炎支原体黏附素基因p97的直系同源基因,并具有与P97蛋白R2区类似的特征性重复序列.通过综合比较分析,推测P113蛋白极可能是绵羊肺炎支原体的黏附素和膜表面免疫原.
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| 关 键 词： | 绵羊肺炎支原体 p113基因 黏附素 免疫原 |
| 收稿时间： | 7/8/2012 12:00:00 AM |
Sequence Analysis and Functional Prediction of Mycoplasma ovipneumoniae p113 Gene |
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| YANG Falong,ZHANG Huanrong,TANG Cheng and YUE Hua.Sequence Analysis and Functional Prediction of Mycoplasma ovipneumoniae p113 Gene[J].Journal of South China Agricultural University,2013,34(1):117-121. |
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| Authors: | YANG Falong ZHANG Huanrong TANG Cheng and YUE Hua |
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| Institution: | College of Life Science and Technology, Southwest University for Nationalities,;College of Life Science and Technology, Southwest University for Nationalities,;College of Life Science and Technology, Southwest University for Nationalities,;College of Life Science and Technology, Southwest University for Nationalities, |
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| Abstract: | The aim of this paper is to conduct a bioinformatics analysis for p113 gene of Mycoplasma ovipneumoniae and further predict its functions. Using several softwares, homology of p113 gene with other genes was calculated and trans-membrane structure, repeat sequence, signal peptide and epitodes were predicted. The results revealed that p113 was an orthologous of Mycoplasma hyopneumoniae adhesin gene pp97 which shared similar R2 repeat sequence. Overall analysis leads to the prediction that P113 protein is one of the important adhesins and membrane immunogens. |
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| Keywords: | Mycoplasma ovipneumoniae p113 gene adhesin immunogen |
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