| 人、猪和鸡血清中抗禽戊型肝炎病毒抗体的检测与鉴定 |
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| 引用本文： | 荆胜涛,张红霞,孙培明,董施伟,赵钦,张璐,周恩民.人、猪和鸡血清中抗禽戊型肝炎病毒抗体的检测与鉴定[J].山东农业大学学报(自然科学版),2010,41(1). |
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| 作者姓名： | 荆胜涛 张红霞 孙培明 董施伟 赵钦 张璐 周恩民 |
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| 作者单位： | 1. 山东农业大学动物医学院,山东省生物技术与疫病防治重点实验室
2. 山东农业大学校医院,山东,泰安,271018 |
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| 基金项目： | 山东省泰山学者基金和家畜疫病病原生物学国家重点实验室(中国农业科学院兰州兽医研究所)开放课题资助 |
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| 摘 要： | 通过对人、猪和鸡血清中的抗禽戊型肝炎病毒(hepatitis E virus, HEV)ORF2抗体的检测以及对阳性血清抗体特异性的鉴定,本研究结果表明,人、猪和禽血清中抗禽HEV ORF2抗体阳性率为0.91%～62.5%.因为禽与哺乳动物HEV ORF2抗原具有共有的抗原表位,而阳性血清中抗禽HEV ORF2特异性抗原表位抗体的阳性率为41.3%～92.1%,提示人、猪和鸡都有感染禽HEV的可能性,这为进一步验证禽HEV可能造成的人兽共感染提供新的科学依据.
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| 关 键 词： | 戊型肝炎病毒 禽戊型肝炎病毒 禽戊型肝炎病毒特异性抗体 血清学调查 |
DETECTION AND CHARACTERIZATION OF HUMAN,SWINE,DUCK AND CHICKEN SERUM ANTIBODIES AGAINST AVIAN HEPATITIS E VIRUS |
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| JING Sheng-tao,ZHANG Hong-xia,SUN Pei-ming,DONG Shi-wei,ZHAO Qin,ZANG Lu,ZHOU En-min.DETECTION AND CHARACTERIZATION OF HUMAN,SWINE,DUCK AND CHICKEN SERUM ANTIBODIES AGAINST AVIAN HEPATITIS E VIRUS[J].Journal of Shandong Agricultural University,2010,41(1). |
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| Authors: | JING Sheng-tao ZHANG Hong-xia SUN Pei-ming DONG Shi-wei ZHAO Qin ZANG Lu ZHOU En-min |
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| Institution: | JING Sheng-tao1,ZHANG Hong-xia2,SUN Pei-ming1DONG Shi-wei1,ZHAO Qin1,ZANG Lu1,ZHOU En-min1*(1.College of Animal Science , Technology,Sh,ong Agricultural University,2.Hospital of Sh,ong Agricultural University,Taian 271018,China) |
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| Abstract: | This study described the serological investigation of avian hepatitis E by testing human,swine and chicken serum antibodies against avian hepatitis E virus(HEV) ORF2 and characterization of the serum antibody specificities.The results demonstrated that the positive rates of human,swine and chicken serum antibody against avian HEV ORF2 antigen were from 0.91% to 62.5%.Because avian and mammalian HEV ORF2 share common epitopes,and the positive rate of specific antibodies against avian HEV ORF2 epitopes were f... |
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| Keywords: | Hepatitis E virus avian hepatitis E virus anti-avian HEV specific antibodies serological investigation |
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