热应激对鸡免疫应答的影响

用ＩＳＡ蛋雏研究２７～３８℃昼夜节律高温对新城疫（ＮＤ）疫苗和传染性法氏囊病（ＩＢＤ）疫苗活苗免疫后体液免疫反应的影响，结果表明：ＮＤ苗或ＩＢＤ苗免疫后立即产生热应激，不论ＮＤ的ＨＩ抗体水平还是ＥＬＩＳＡ抗ＩＢＤ抗体滴度在整个实验过程中均受到显著抑制（Ｐ＜０．０５）；应激后立即免疫ＮＤ疫苗或ＩＢＤ疫苗的鸡，ＨＩ抗体水平在免疫后第５和１４天和ＥＬＩＳＡ抗体滴度在免疫后第９天和１６天与对照组相比显著降低（Ｐ＜０．０５）；应激后２４小时免疫，或免疫后２４小时至若干天遭受高温应激的鸡，抗ＮＤ和ＩＢＤ抗体水平分别在免疫后第１４天和１６天均受到显著抑制（Ｐ＜０．０５）。试验组免疫器官与体重之比与对照组间无显著性差异，但免疫器官的组织学结构都有明显的坏死和萎缩性变化

Effect of Heat Stress on the Immune Response of Chicken

ISA chickens were conducted to inveestigate the effect of heat stress on the immune response to viable ND or IBD vaccine,The temperature was simulated the cyclic diurnal scale for the summer in the south of China.the results showed that HI anti-ND Ab titers of ELISA anti-IBD Ab titers were significantly reduced (P<0.05)in bird exporsed to high temperature immediatly after ND or IBD vaccine being administrated.The HI anti-ND Ab titers of the 5th and 14th day postimmunization(PI) or ELISA anti-IBD AB titers of 9th and 16th day PI were observed significantly lower (P<0.05) compared with contrast.the anti-ND Ab or anti-IBD Ab titers of chickens which were stressed 24 hours before or stressed after immunization or several days after immunization were depressed significantly at 14th and 16th day PI respectively(P<0.05).There were no significantly differecens in the indices of immune organs (thymus,bursa and spleen) weight to body weight for all treatment groups compared with contrast.Atrophy and lymphocyte necrosis were observed in the microscopic structure of immune organs of all stressed groups.