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狗舌草总黄酮的提取及其毒性试验
引用本文:司红丽,王建华,王跃虎. 狗舌草总黄酮的提取及其毒性试验[J]. 畜牧与兽医, 2003, 35(7): 9-10
作者姓名:司红丽  王建华  王跃虎
作者单位:西北农林科技大学动物科技学院,陕西,杨凌,712100
基金项目:中国杨凌农业高科技示范区科技专项基金 1999KG13
摘    要:
从狗舌草中提取分离到黄酮类化合物并测定其含量 ,用改良寇氏法测定总黄酮的小鼠LD50 为 ( 1392 52± 94 6 2 )mg/kg ,属于中等毒范围。初步表明其与临床牧区的狗舌草中毒病相关不大 ,可能与狗舌草的抗癌、抑癌作用有关

关 键 词:狗舌草  黄酮类化合物  LD_(50)  毒性
文章编号:0529-5130(2003)07-0009-02

Extraction and toxicity of Flavonoids from Tephroseris kirilowii
SI Hong li,WANG Jian hua,WANG Yue hu. Extraction and toxicity of Flavonoids from Tephroseris kirilowii[J]. Animal Husbandry & Veterinary Medicine, 2003, 35(7): 9-10
Authors:SI Hong li  WANG Jian hua  WANG Yue hu
Abstract:
In this study, the flavonoids were extracted from Tephroseris kirilowii Turcz Holub, and the contents were determined. The result showed that LD 50 of flavonoids was (1 392 52±94 62) mg/kg(mice,ip),belonging to medial toxicity.It may be not connected with the toxicity of Tephroseris kirilowii in the pastoral areas,but may be related to the anticarcinogene and antitumor activity.
Keywords:Tephroseris kirilowii Turcz Holub  flavonoid  LD 50  toxicity$$$$
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