用平板式超滤机浓缩鸡新城疫病毒及法氏囊病毒试验效果观察

采用ＵＦ１型工业平板式超滤机对鸡新城疫病毒（ＮＤＶ）及法氏囊病毒（ＩＢＤＶ）进行了初步的浓缩试验。该设备浓缩工艺简单、效率高，浓缩液ＨＡ效价与未浓缩液比较按浓缩比率相应上升。用浓缩液与未浓缩液制成灭活疫苗免疫鸡，均可获得１００％抵抗ＮＤ及ＩＢＤ的保护力，以浓缩苗免疫的ＮＤＨＩ抗体及ＩＢＤ中和抗体滴度明显高于未浓缩苗。试验表明，浓缩苗安全有效，并优于未浓缩苗。

Experiments of Concentrating NDV and IBDV by Using Plate-type Ultrafilter

Preliminary experiments of concentrating NDV and IBDV were carried out by using an industrial platetype UF1 model ultrafilter. The equipment was simple in operating process and high in efficency of concentrating viruses. The HA titers of the concentrated virus fluids were higher than those of the unconcentrated virus fluids, and were proportional to the increase of concentration. The inactivated oiladjuvant vaccines were prepared by using concentrated virus fluids and unconcentrated virus fluids. All chickens treated with concentrated vaccins and unconcentrated vaccines could gain 100% protection against virulent NDV and IBDV challenges. Both NDV HI and IBDV VN antibody titers of chickens treated with concentrated vaccinse were much higher than those treated with unconcentrated vaccines. The experimental results indicated that the concentrated vaccine was safer and better than the unconcentrated vaccine.