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| 禽流感母源抗体消长规律和免疫保护抗体临界值的测定 | |
| 引用本文： | 吴庭才,张春杰,郭向鹏. 禽流感母源抗体消长规律和免疫保护抗体临界值的测定[J]. 河南科技大学学报(农学版), 2002, 22(4): 243-244 |
| 作者姓名： | 吴庭才 张春杰 郭向鹏 |
| 作者单位： | 河南科技大学,河南,洛阳,471003 |
| 摘 要： | 对初生雏鸡的AI母源抗体进行了动态观察 ,并在HI效价为 6 (Log2 )和 4 (Log2 )、2 (Log2 )左右时 ,分别应用禽流感病毒进行攻毒。结果显示 :初生雏鸡AI母源抗体HI效价的峰值在 7日龄时 (7.85 (Log2 ) )出现 ,比 1日龄 (6 .8(Log2 ) )时高出 1个倍比滴度 ;7日龄后HI效价即随雏鸡日龄的增加而迅速下降 ;至 2 8日龄时 ,已趋于消失。攻毒试验中 ,当HI效价为 6 (Log2 )左右时 ,其保护率为 10 0 % ;在 4 (Log2 )时 ,保护率仅为 5 0 % ;在 2 (Log2 )左右时 ,保护率只有2 0 %。由此说明 ,能使雏鸡对AIV的攻击获得完全保护的临界值应在 4 (Log2 )～ 6 (Log2 )之间 ,且必须大于 4 (Log2 )。 |
| 关 键 词： | 禽流感 母源抗体 临界值 |
| 文章编号： | 1008-4673(2002)04-0243-02 |
| 修稿时间： | 2002-06-17 |
Determination on the decreasing rule of the maternal HI antibody and the lowest HI titer protected new-birth chicken against AIV |
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| WU Ting cai,ZHANG Chun jie,GUO Xiang peng. Determination on the decreasing rule of the maternal HI antibody and the lowest HI titer protected new-birth chicken against AIV[J]. Journal of Henan University of Science and Techno, 2002, 22(4): 243-244 | |
| Authors: | WU Ting cai ZHANG Chun jie GUO Xiang peng |
| Abstract: | Avian influenza(AI)maternal HI antibody were tested regularly in new birth chicken,and when the average HI titers were 6Log2?4Log2 and 2Log2,chicken were challenged with AIV separately.The results showed that the peak of HI titer(7.85Log2)appeared on the 7th day.It was higher one times than HI titer on the 1st day(6.8Log2).After the 7th day,the HI titer decreased fast with the chicken growing.Until the 28th day,HI antibody vanished fundamentally.When HI titers were 6Log2?4Log2 and2Log2,the protective rate were 100%?50%?20%respectively. It can be concluded that the lowest HI titer which can prevent chicken from AIV should be 4Log2 to 6Log2,and must be higher than 4Log2. |
| Keywords: | AI maternal antibody lowest HI titer |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |