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胶体金免疫层析技术在兽医临床中的应用
引用本文:张玉雪,伍钢,韦佳塔,刘琪琦,陈海兰.胶体金免疫层析技术在兽医临床中的应用[J].动物医学进展,2020(6):120-123.
作者姓名:张玉雪  伍钢  韦佳塔  刘琪琦  陈海兰
作者单位:广西大学动物科学技术学院;军事医学研究院辐射医学研究所
基金项目:广西自然科学基金项目(2016GXNSFBA380053);国家科技重大专项(2018ZX10711001-003-003)。
摘    要:胶体金免疫层析技术(GICA)是将胶体金作为示踪物应用于硝酸纤维素膜上,在特定位置发生抗原抗体特异性反应信号的一种快速检测技术,以简便快速、成本低廉、安全无毒、特异性强等优点广泛应用于兽医临床检测。论文首先总结了GICA在动物疾病诊断和动物源性食品安全检验中的应用,然后综述了GICA新型标记材料和新技术的结合与应用,最后展望了GICA在兽医临床应用的发展趋势。

关 键 词:胶体金  免疫层析  动物疾病  食品安全  快速检测

Application of Colloidal Gold Immunochromatography Assay in Veterinary Clinic
ZHANG Yu-xue,WU Gang,WEI Jia-ta,LIU Qi-qi,CHEN Hai-lan.Application of Colloidal Gold Immunochromatography Assay in Veterinary Clinic[J].Progress In Veterinary Medicine,2020(6):120-123.
Authors:ZHANG Yu-xue  WU Gang  WEI Jia-ta  LIU Qi-qi  CHEN Hai-lan
Institution:(College of Animal Science and Technology,Guangxi University,Nanning,Guangxi,530005,China;Beijing Institute of Radiation Medicine,Beijing,100850,China)
Abstract:Colloidal gold immunochromatography assay(GICA)is a new rapid detection technology using colloidal gold as tracers for the visualization of the antigen-antibody reaction at the specific area of nitrocellulose(NC)filter membrane.Due to its characteristics of simple,rapid,low cost,safe and specific,GICA has been widely used in veterinary clinical testing.In this paper,the application of GICA in animal disease diagnosis and animal food safety test were firstly summarized.Then,the combination of GICA with new materials and new detection technology was reviewed.Finally,the future trend for GICA development in veterinary clinical applications was suggested.
Keywords:colloidal gold  immunochromatography  animal diseases  food safety  rapid detection
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