Gastrointestinal Lymphoma in 20 Dogs

The records of 20 dogs with histopathologically diagnosed gastrointestinal (GI) lymphoma (LSA) evaluated between 1970 and 1984 were reviewed. Fifteen dogs were considered to have primary GI LSA, while five dogs had GI involvement in association with the multicentric form. Most clinical and laboratory findings were nonspecific, but positive-contrast upper GI radiography was suggestive of GI LSA in all of the dogs evaluated. Nine dogs had extensive lymphocytic-plasmacytic inflammatory infiltrates around the neoplastic foci, resulting in difficulty in obtaining a diagnosis of GI LSA when samples were obtained by endoscopy.