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Structure of a novel diterpenoid ester,fritillahupehin from bulbs of Fritillaria hupehensis Hsiao and K.C. Hsia
Authors:Ruan Hanli  Zhang Yonghui  Wu Jizhou  Deng Shukai  Sun Handong  Fujita Tetsuro
Institution:Faculty of Pharmaceutical Sciences, Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430030, PR China. ruanhl@27.net
Abstract:A new diterpenoid ester, fritillahupehin (1) together with three known fatty acids: palmitic acid (2), lignoceric acid (3) and azelaic acid (4) were isolated from the bulbs of Fritillaria hupehensis Hsiao and K.C. Hsia. The structure of fritillahupehin has been established to be ent-kauran-16beta-yl lignocerate by means of spectroscopic and chemical evidence. Compounds 2-4 were isolated from Fritillaria sp. for the first time.
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