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维生素D对动物免疫细胞的调节作用
引用本文:李思明,欧阳玲花,韦启鹏,谷德平,李华伟,肖卫华,郭田华.维生素D对动物免疫细胞的调节作用[J].江西农业学报,2011,23(12):147-149.
作者姓名:李思明  欧阳玲花  韦启鹏  谷德平  李华伟  肖卫华  郭田华
作者单位:1. 江西省农业科学院畜牧兽医研究所,江西南昌,330200
2. 江西省遂川县畜牧兽医局,江西遂川,343900
基金项目:国家自然科学基金,江西省青年科学家培养计划
摘    要:维生素D3能调节和控制免疫细胞的增殖和分化,产生免疫调节作用。1,25-二羟维生素D3是维生素D3的活性形式,其功能研究的进展和免疫调节机制的新认识,提示它们在畜禽免疫营养上增强动物抵抗力具有广泛的应用潜力。1,25-二羟维生素D3除了直接作用于T细胞外,还通过各种机制调节单核细胞、巨噬细胞等免疫细胞的表型和功能。该文综述了维生素D3及其活性形式1,25-二羟维生素D3的细胞免疫调节功能的新认识。

关 键 词:维生素D3  免疫细胞  免疫功能调节

Regulatory Effect of Vitamin D on Immunocytes of Animal
LI Si-ming , OUYANG Ling-hua , WEI Qi-peng , GU De-ping , LI Hua-wei , XIAO Wei-hua , GUO Tian-hua.Regulatory Effect of Vitamin D on Immunocytes of Animal[J].Acta Agriculturae Jiangxi,2011,23(12):147-149.
Authors:LI Si-ming  OUYANG Ling-hua  WEI Qi-peng  GU De-ping  LI Hua-wei  XIAO Wei-hua  GUO Tian-hua
Institution:LI Si - ming , OUYANG Ling - hua , WEI Qi - peng , GU De - ping , LI Hua - wei , XIAO Wei - hua, GUO Tian - hua (1. Institute of Animal Husbandry and Veterinary, Jiangxi Academy of Agricultural Science, Nanchang 330200, China; 2. Suichuan Bureau of Animal Husbandry and Veterinary in Jiangxi Province, Suichuan 343900, China)
Abstract:Vitamin D3 can regulate and control the proliferation and differentiation of immunocytes, and thus has immunity - regulatory activity. 1,25 - (OH) 2 vitamin D3 is the active form of vitamin D3 , and the new research progress and new knowledge in the function and immunity - regulatory mechanism of 1,25 - (OH) 2 vitamin D3 prompt that it has extensive application potential in strengthening the resistance of animals through immune nutrition. 1,25 - (OH) 2 vitamin D3 can not only directly act on T -cell, but also regulate the phenotype and function of immunocytes, such as monocyte and macrophage, through some mechanisms. The paper summarized the new knowledge of inmaunity -regulatory function of vitamin D3 and its active form 1,25 - (OH) 2 vitamin D3.
Keywords:Vitamin D3  Immunocyte  Immunity regulation
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