环丙沙星的临床应用与合理用药

环丙沙星是第3 代喹诺酮类抗菌作用较强的药物,抗菌谱广,对细菌、支原体都有强烈的抑制和杀灭作用,对临床分离的一些耐青霉素类、头孢菌素类、氨基糖苷类抗生素的菌株也有较强的抗菌活性。临床上广泛用于控制由敏感病原体引起的胃肠道感染、肺部感染、泌乳和生殖系统感染和局部感染等,也用于水生动物和家禽的疾病防治。文章就其抗菌谱、临床应用、与其他抗菌药的联合应用以及不良反应等方面进行综述。

Clinical Applications and Rational Use of Ciprofloxacin

Ciprofloxacin is stronger than other antibaterials in the third generation of quinolones. It has broad-spectrum antibacterial activity. Ciprofloxacin has excellent activity against bacteria and mycoplasmas, including many organisms resistant to penicillins, cephalosporins and aminoglycosides. So it is applied for the treatments of a wide variety of infectious diseases, such as gastrointestinal tract, pulmonary, obstetric, local infection, and so on. Ciprofloxacin is also applied to prevent and cure the infectious diseases of aquatic animal and poultry. The antibacterial spectrum,clinical applications,combination use with other antibacterial, and side reactions of ciprofloxacin are summarized in this paper.