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脂肪酸移位酶CD36/SR-B2及其介导的长链脂肪酸跨膜转运
引用本文:骆东梅,汪水平,赵雪莉,韩雪峰. 脂肪酸移位酶CD36/SR-B2及其介导的长链脂肪酸跨膜转运[J]. 动物营养学报, 2019, 0(6): 2552-2559
作者姓名:骆东梅  汪水平  赵雪莉  韩雪峰
作者单位:西南大学动物科学学院;中国科学院亚热带农业生态研究所亚热带农业生态过程重点实验室畜禽养殖污染控制与资源化技术国家工程实验室湖南省畜禽健康养殖工程技术研究中心农业部中南动物营养与饲料科学观测实验站;习水富兴牧业有限公司;白玉县牧旺农业科技有限公司;白玉玉牧丰源畜牧科技有限公司
基金项目:国家自然科学基金项目(31872386);四川省科技计划项目(2019YFN0080);四川省政府采购项目(5133312018000053)
摘    要:长链脂肪酸是维持机体正常代谢的重要营养素,其吸收、转运和代谢对动物的健康、生长和生产具有重要意义。近年来,研究发现一些脂肪酸转运蛋白介导长链脂肪酸的跨膜转运。脂肪酸移位酶CD36/SR-B2是一种整合膜蛋白,能特异性介导脂肪酸在多种细胞中的跨膜转运。本文对CD36/SR-B2的由来、亚细胞定位、功能调控及其介导的长链脂肪酸跨膜转运进行概述,探讨其对脂质代谢的调控机制。

关 键 词:脂肪酸移位酶  CD36/SR-B2  长链脂肪酸  跨膜转运

Fatty Acid Translocase CD36/SR-B2 and Its Mediation in Transmembrane Transportation of Long-Chain Fatty Acids
LUO Dongmei,WANG Shuiping,ZHAO Xueli,HAN Xuefeng. Fatty Acid Translocase CD36/SR-B2 and Its Mediation in Transmembrane Transportation of Long-Chain Fatty Acids[J]. CHINESE JOURNAL OF ANIMAL NUTRITION, 2019, 0(6): 2552-2559
Authors:LUO Dongmei  WANG Shuiping  ZHAO Xueli  HAN Xuefeng
Affiliation:(College of Animal Science,Southwest University,Chongqing 402460,China;Key Laboratory for Agri-EcologicalProcesses in Subtropical Region,National Engineering Laboratory for Pollution Control and Waste Utilization inLivestock and Poultry Production,Hunan Research Center of Livestock and Poultry Sciences,South CentralExperimental Station of Animal Nutrition and Feed Science in Ministry of Agriculture,Institute ofSubtropical Agriculture,The Chinese Academy of Sciences,Changsha 410125,China;XishuiFuxing Husbandry Co.,Ltd.,Xishui 556400,China;Baiyu Muwang Agricultural Science andTechnology Co.,Ltd.,Baiyu 627150,China;Baiyu Yumu Fengyuan Animal HusbandryScience and Technology Co.,Ltd.,Baiyu 627150,China)
Abstract:LUO Dongmei;WANG Shuiping;ZHAO Xueli;HAN Xuefeng(College of Animal Science,Southwest University,Chongqing 402460,China;Key Laboratory for Agri-EcologicalProcesses in Subtropical Region,National Engineering Laboratory for Pollution Control and Waste Utilization inLivestock and Poultry Production,Hunan Research Center of Livestock and Poultry Sciences,South CentralExperimental Station of Animal Nutrition and Feed Science in Ministry of Agriculture,Institute ofSubtropical Agriculture,The Chinese Academy of Sciences,Changsha 410125,China;XishuiFuxing Husbandry Co.,Ltd.,Xishui 556400,China;Baiyu Muwang Agricultural Science andTechnology Co.,Ltd.,Baiyu 627150,China;Baiyu Yumu Fengyuan Animal HusbandryScience and Technology Co.,Ltd.,Baiyu 627150,China)
Keywords:fatty acid translocase  CD36/SR-B2  long-chain fatty acids  transmembrane transportation
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