| 哺乳类动物胚胎干细胞多能性和全能性研究进展 |
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| 引用本文： | 安立龙,杨奇,雷安民,窦忠英.哺乳类动物胚胎干细胞多能性和全能性研究进展[J].西北农业学报,1999,8(2):113-116. |
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| 作者姓名： | 安立龙 杨奇 雷安民 窦忠英 |
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| 作者单位： | 西北农业大学家畜生殖内分泌与胚胎工程农业部重点开放实验室, 陕西杨陵 712100;西北农业大学家畜生殖内分泌与胚胎工程农业部重点开放实验室, 陕西杨陵 712100;西北农业大学家畜生殖内分泌与胚胎工程农业部重点开放实验室, 陕西杨陵 712100;西北农业大学家畜生殖内分泌与胚胎工程农业部重点开放实验室, 陕西杨陵 712100 |
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| 摘 要： | 交ＥＳ细胞分离与克隆技术和分子生物学技术相结合就可将新的遗传物质导入家畜的生殖腺细胞。通过囊胚注入胚胎干细胞产生嵌合体小鼠表明对胚胎干细胞进行遗传操作是对物生殖细胞进行遗传改造的有效方法之一。
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| 关 键 词： | 胚胎干细胞 全能性 嵌合 核移植 生殖细胞 |
| 收稿时间： | 1997/12/10 0:00:00 |
| 修稿时间： | 1998/11/24 0:00:00 |
Progress on Totipontency and Multipotentiality of Embryonic Stem in Mammalian |
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| AN Lilong,YANG Qi,LEI Anmin and DOU Zhongying.Progress on Totipontency and Multipotentiality of Embryonic Stem in Mammalian[J].Acta Agriculturae Boreali-occidentalis Sinica,1999,8(2):113-116. |
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| Authors: | AN Lilong YANG Qi LEI Anmin and DOU Zhongying |
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| Institution: | Open and Key Labratory of Domestic Animal Reproductive Endocrinology and Embronic Engineering, Agricultural Ministry of China, Northwestern Agricutural University, Yangling Shaanxi 712100;Open and Key Labratory of Domestic Animal Reproductive Endocrinology and Embronic Engineering, Agricultural Ministry of China, Northwestern Agricutural University, Yangling Shaanxi 712100;Open and Key Labratory of Domestic Animal Reproductive Endocrinology and Embronic Engineering, Agricultural Ministry of China, Northwestern Agricutural University, Yangling Shaanxi 712100;Open and Key Labratory of Domestic Animal Reproductive Endocrinology and Embronic Engineering, Agricultural Ministry of China, Northwestern Agricutural University, Yangling Shaanxi 712100 |
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| Abstract: | The new genetic material can introduce into germ cell in faun aninal by the combination of embryonic stem culturewith molecular biological techniques genetic manipulation of embryonic stem (ES) cell in culture to produce chinericmouse by bastocyts injectection has proved a powerfull tool for germ line manipulation.The detective techniques of multipontentialicy or totipontency in ES cell were an inportant method to inprove aninal The applications of ES cell in studies of cloning aninal, gene engineering and development biology were vast vista. |
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| Keywords: | Embryonic stem cell Totipotency Multipotentiality Chimera Nuclear Transfer Germ line genetic modification |
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