| 实验性犬传染性肝炎肝胆的扫描电镜和透射电镜观察 |
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| 引用本文： | 崔龙波. 实验性犬传染性肝炎肝胆的扫描电镜和透射电镜观察[J]. 中国兽医学报, 1988, 0(3) |
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| 作者姓名： | 崔龙波 |
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| 作者单位： | 兽医大学军事兽医研究所 |
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| 摘 要： | 透射电镜下,犬传染性肝炎急性坏死型病例肝细胞线粒体高度肿胀,嵴断裂。病变严重的,肝细胞胞浆固有结构崩解、碎裂。核内包涵体由基质和ICHV粒子构成;在不含包涵体的核内也见到ICHV粒子。核内的ICHV粒子通过溶解的核膜或由于核崩解而释入胞浆;当细胞膜局部破裂或整个细胞崩解时,细胞内的ICHV粒子释放于细胞外。在嗜酸性小体的胞浆内观察到ICHV粒子。窦状隙内皮细胞和星状细胞呈现与肝细胞类似的变化。扫描电镜下,组织学呈凝固性坏死的胆囊粘膜袁面平坦无结构;亦见胆囊粘膜有局部灶坏死,与周围界限明显,坏死灶外围的上皮细胞结结构不整,上皮顶部凸出的颗粒大小不一或脱落。透射电镜下,呈坏死的胆囊粘膜上皮细胞固有结构消失,呈均质状;其余部位的上皮细胞微绒毛断裂、脱落;线粒体肿胀,嵴溶解,上皮顶部堆集大量的致密小体,细胞间连接复合体结构消失;亦见血管均质坏死,血管内皮的坏死与粘膜上皮的坏死同步或先于其发生。
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| 关 键 词： | 犬传染性肝炎 肝脏 胆囊 超微结构 |
Observations on the Liver and Calldladder of Dogs Infected Artificially with Infectious Canine Hepatitis by Scanning and Transmission Electron Microscopy |
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| Cui Longbo. Observations on the Liver and Calldladder of Dogs Infected Artificially with Infectious Canine Hepatitis by Scanning and Transmission Electron Microscopy[J]. Chinese Journal of Veterinary Science, 1988, 0(3) |
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| Authors: | Cui Longbo |
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| Abstract: | The ultrastructural changes of the liver and gallbladder in dogs infected with artificially infectious canine hepatitis were described in this paper. In addition, the mechanisms of duplication and release of the virus particles in liver were discussed. |
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| Keywords: | infectious canine hepatitis liver gallbladder ultrastructure |
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