Identification of growth hormone receptor in the ovary of tilapia, Oreochromis mossambicus |
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| Authors: | S Kajimura N Kawaguchi K Kawazoe K Okubo K Aida |
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| Institution: | 1. Graduate School of Agricultural and Life Sciences, University of Tokyo, Tokyo, 113-8657, Japan
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| Abstract: | Growth hormone receptor (GH-R) cDNA was isolated and characterized in the tilapia, Oreochromis mossambicus. GH-R mRNA was expressed in the nucleus and cytoplasm of the young oocytes and in the follicles surrounding vitellogenic oocytes showing a correlation with ovarian IGF-I mRNA levels. However, no change was seen in liver GH-R/IGF-I mRNA levels or plasma GH/IGF-I levels during ovarian development, suggesting that GH/IGF-I axis may be involved in the ovarian development in paracrine or autocrine manner, independent of liver derived IGF-I. |
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