胡桃醌及其衍生物5,8-二羟基-1,4-萘醌抑菌活性研究

以红景天立枯病菌(Rhizoctonia solani Kühn)等12种病原真菌为供试靶标,测试了胡桃醌(5-羟基-1,4-萘醌)及其衍生物5,8-二羟基-1,4-萘醌的抑菌活性。结果表明:两者对丝核菌属病原真菌菌丝生长的抑制作用大于镰刀属,对3种丝核菌属病原真菌的EC₅₀分别为10.63～15.88mg/L、9.79～14.69mg/L;两者对玉米小斑病菌孢子萌发的抑制作用最高,在12.5mg/L时,抑制率均达到60%以上;在50mg/L时,对镰刀属4种病原真菌孢子萌发抑制率均达到60%。

Antifungal activity of juglone and its derivative 5,8-dihydroxy-1,4-naphthoquinone

The antifungal activity of juglone and its derivative,5,8-dihydroxy-1,4-naphtho-quinine,was tested against 12 pathogenic fungi.Both of the compounds showed higher inhibition effects on the growth of the mycelia of Rhizoctonia than on that of Fusarium oxysporum f.sp.The EC50 values of juglone and 5,8-dihydroxy-1,4-naphthoquinine against the 3 fungi of Rhizoctonia were 10.63-15.88 mg /L and 9.79-14.69 mg /L,respectively.Both of them exhibited the highest inhibitory effects on conidial germination of Bipolaris maydis,and their inhibitory rates were more than 60% at the concentration of 12.5 mg /L.The inhibitory rates of the 4 pathogenic fungi of Fusarium were about 60% at the dosage of 50 mg /L.