|
|||||
|
|
| RNAi-基因沉默的分子机理 | |
| 引用本文： | 耿波,曹顶臣,孙效文,欧阳红生.RNAi-基因沉默的分子机理[J].水产学杂志,2005,18(2):83-88. |
| 作者姓名： | 耿波 曹顶臣 孙效文 欧阳红生 |
| 作者单位： | 1. 中国水产科学研究院黑龙江水产研究所,黑龙江,哈尔滨,150070;吉林大学,吉林,长春,130062 2. 中国水产科学研究院黑龙江水产研究所,黑龙江,哈尔滨,150070 3. 吉林大学,吉林,长春,130062 |
| 摘 要： | 本文介绍了RNA干扰造成基因沉默的几种小分子RNA的类型和作用机理，以及RNA干扰的应用前景及不同方法合成的小分子RNA对动物机体免疫系统的影响。 |
| 关 键 词： | RNA干扰 基因沉默 小分子RNA |
| 文章编号： | 1005-3832(2005)02-0083-06 |
| 收稿时间： | 08 8 2005 12:00AM |
| 修稿时间： | 2005年8月8日 |
The molecular mechanism involved in RNAi |
|
| GENG Bo,CAO Ding-chen,SUN Xiao-wen,OU Yang-hong-Sheng.The molecular mechanism involved in RNAi[J].Chinese Journal of Fisheries,2005,18(2):83-88. | |
| Authors: | GENG Bo CAO Ding-chen SUN Xiao-wen OU Yang-hong-Sheng |
| Institution: | 1. Hei Longjiang Institute of Fishery, Chinese Academic of Fishery, Harbin 150070, China; 2. Jilin University, Changehun 130062, China |
| Abstract: | This article introduced several types of micro RNAs which result in the gene silence and the mechanism of function. This article also refered to the prospects of RNAi and the inflluence of different miro RNAs synthetized by different methods to animal immunity system. There have four type short RNAs including siRNAs, miRNAs, tncRNAs and smRNAs, which they all play an importance pole on the mRNA expression in cells and can use to therapy some diseases induced by virus. |
| Keywords: | RNA interference gene silence micro RNA |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |