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Manufacturing technique and mechanical properties of polylactide acid net/chitosan composite membrane |
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| Authors: | Ching-Wen Lou Ming-Gene Tu Chao-Tsang Lu Po-Ching Lu Jia-Horng Lin |
| Affiliation: | 1. Institute of Biomedical Engineering and Materials Science, Central Taiwan University of Science and Technology, Taichung, 40601, Taiwan, R.O.C. 2. School of Dentistry, China Medical University, Taichung, 40402, Taiwan, R.O.C. 3. Department of Dentistry, China Medical University Hospital, Taichung, 40402, Taiwan, R.O.C. 4. Graduate Institute of Biotechnology, Central Taiwan University of Science and Technology, Taichung, 40601, Taiwan, R.O.C. 5. Laboratory of Fiber Application and Manufacturing, Department of Fiber and Composite Materials, Feng Chia University, Taichung, 40724, Taiwan, R.O.C. 6. School of Chinese Medicine, China Medical University, Taichung, 40402, Taiwan, R.O.C. 7. Department of Fashion Design, Asia University, Taichung, 41354, Taiwan, R.O.C. |
| Abstract: | Guided tissue regeneration is an important treatment for periodontal diseases, as it helps periodontal tissues to regenerate. This study aims to evaluate the influence of different procedures for gelation on the mechanical properties of low melting-point polylactic acid (LPLA) net/chitosan composite membranes. After immersion in a chitosan solution, LPLA nets undergo different steps of gelation and freeze-drying, forming the porous LPLA/Chitosan composite membranes. The tensile strength, swelling, degradation and water content of the resulting membranes are then evaluated. According to the experimental results, different sequences for gelation influence the tensile strength and swelling ratio, but do not significantly influence the water content ratio and contact angle. |
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