载铜蒙脱石对断奶仔猪生长性能及血清免疫指标、抗氧化指标、炎症指标的影响

本试验旨在研究饲粮中添加载铜蒙脱石对断奶仔猪生长性能及血清免疫、抗氧化、炎症等生化指标的影响.选取72头(25±3)日龄、体重为(7.42±0.88)kg的健康仔猪(公母各半),按随机区组设计分为3组,每组4个重复,每个重复6头猪.3个处理分别为对照组、氧化锌+抗生素组及载铜蒙脱石组,对照组饲喂基础饲粮,氧化锌+抗生素...

Effect of Copper-Bearing Montmorillonite on Growth Performance,Serum Immune Index,Antioxidant Index and Inflammation Index of Weaned Piglets

This study aimed to investigate the effects of copper-bearing montmorillonite on growth performance, serum immune indices, antioxidant index and inflammation index of weaned piglets. A total of twenty two healthy piglets(25±3 days, half barrows and half gilt) with body weight of 7.42±0.88 kg were randomly allotted to 4 blocks with three treatment in each block and 6 piglets per treatment. The three treatment were namely control group(CTR group), zinc oxide + antibiotic group(ZnO+ATB group), copper-bearing montmorillonite group(CSN group). CTR fed with basal diet, ZnO + ABT fed with basal diet supplied 1600 mg/kg ZnO + 75 mg/kg chlorotetracycline +20 mg/kg kitasamycin during 0-14 d, and basal diet with75 mg/kg chlorotetracycline +20 mg/kg kitasamycin during 14-28 d. CSN group fed with basal diet supplied 0.16% copper-bearing montmorillonite. The whole experiment lasted for 28 d. The results showed that compared to CTR, body weight of ZnO+ATB and CSN group markedly increased on 14 d and 28 d, average daily gain(ADG) increased during 0-28 d, and feed gain ratio decreased during 0-14 d(P<0.05). As compared to CTR, serum malondialdehyde content of CSN group decreased(P<0.05). while no differences were observed on immune index among the three groups. Fed with ZnO+ATB or CSN markedly decreased serum concentration of diamine oxidase, interleukin-1β, interleukin-6, tumor necrosis factor-α(P<0.05). Meanwhile, CSN decreased serum content of interleukin-6. These results suggested that supplementation of 0.16% copper-bearing montmorillonite can promote the growth performance, improve host antioxidation competence and decrease inflammation response of weaned piglets.