痒螨诱导宿主免疫应答研究进展

痒螨病普遍存在于世界各地,严重危害着动物的健康,也给动物养殖业造成巨大的经济损失。痒螨在宿主体表的物理活动、分泌物及其死亡后的瓦解产物,可激活宿主的一系列复杂级联反应,最终导致宿主的局部和系统性炎症反应及免疫应答。目前,国内外学者对痒螨的流行病学、治疗等方面研究较多,但在痒螨引起宿主的免疫应答方面研究相对较少。论文就动物感染痒螨后其组织和血液内炎性细胞的变化情况及痒螨诱导宿主发生的免疫应答——超敏反应、体液免疫应答和细胞免疫应答等方面进行综述。

Progress on Immune Responses of Hosts Induced by Psoroptic mites

Psoroptic mange is prevalent worldwide and seriously endangers the animal production as well as animal health,causing huge economic losses to the animal industry.The physical activity,excretory and secretory products,collapse products of psoroptic mites on the hosts can activate a series of complex cascade responses of hosts,eventually leading to local and systemic inflammatory responses and immune responses.At present,the domestic and foreign scholars mainly study the epidemiology,treatment and other aspects of psoroptic mites,but the immune responses of the host caused by psoroptic mites are relatively few.This paper summarized the changes of inflammatory cells in infected animal tissues and blood and immune responses of hosts induced by psoroptic mites including hypersensitivity,humoral immune response and cellular immune response.