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Dietary supplementation with Chinese herbal ultra-fine powder enhances cellular and humoral immunity in early-weaned piglets |
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| Authors: | X.F. Kong G.Y. Wu Y.P. Liao Z.P. Hou H.J. Liu F.G. Yin T.J. Li R.L. Huang Y.M. Zhang D. Deng M.Y. Xie Z.Y. Deng H. Xiong Z. Ruan P. Kang C.B. Yang Y.L. Yin M.Z. Fan |
| Affiliation: | aThe key Laboratory of Food Science of Ministry of Education, Department of Food Science & Engineering, Nanchang University, Jiangxi, Nanchang 330047, China bLaboratory of Animal Nutrition and Health and Key Laboratory of subtropical Agro-ecology, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha, Hunan, 410125, China cDepartment of Animal Science, Texas A&M University, College Station, TX, 77843, USA dCentre for Nutrition Modelling, Departments of Animal and Poultry Science, University of Guelph, Guelph, Ontario, Canada N1G 2V7 |
| Abstract: | This study was conducted to determine effects of dietary supplementation with a Chinese herbal ultra-fine (CHU) powder on cellular and humoral immunity in early-weaned piglets. Sixty piglets weaned at 21 days of age were randomly assigned to one of 3 treatment groups representing supplementation with 0 or 2 g/kg of the powder, or 0.2 g/kg of colistin (an antibiotic) to maize- and soybean meal-based diets (n = 20). On days 7, 14 and 28 after initiation of the treatment, lymphocyte proliferating activity and serum levels of antibodies and cytokines were measured. Results indicated that the powder enhanced (P < 0.05) serum concentrations of IL-2, IL-6 and TNF- on days 7 and 28, and of IgG and IgM on day 28, as well as the proliferating activity of blood lymphocytes in vivo on all days relative to the none additive group. Addition of the powder (7.82 to 31.25 mg/ml) to culture medium in vitro also increased (P < 0.05) the proliferating activity of blood lymphocytes compared with the none additive group. These findings indicate a beneficial effect of the CHU powder on cellular and humoral immune responses in piglets. |
| Keywords: | Dietary additive Chinese herbs Immunity Early-weaned piglets |
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