Study on Expression of Insulin-like Growth Factor-binding Protein -3 and -5 (IGFBP-3 and IGFBP-5) in the Skin of Inner Mongolia Cashmere Goat |
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| Authors: | YU Xin-lei CAI Ting JU Hong-li YANG Hui-ru XIAO Hong-mei LIU Zhi-hong WANG Quan-xi WANG Zhi-xin LI Jin-quan |
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| Institution: | 1. Inner Mongolia Key Laboratory of Animal Genetics, Breeding and Reproduction, Inner Mongolia Agricultural University, Hohhot 010018, China;2. Graduate School, Inner Mongolia Agricultural University, Hohhot 010018, China |
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| Abstract: | This experiment was conducted to study the expression effect of insulin-like growth factor-binding protein(IGFBP) of Inner Mongolia Cashmere goat skin in different developmental stage. The expression of IGFBP-1 to IGFBP-6 in different developmental stage of hair follicle cycle was measured by Real-time PCR. Furthermore, the hair growth cycle was changed by implanting melatonin to identify the role of IGFBP-1 to IGFBP-6 gene, the high expression of the binding protein. The results showed that IGFBP-3 and IGFBP-5 both were expressed in different developmental stage of hair follicle cycle, however, the expression of IGFBP-5 gene presented more regular. The results indicated that IGFBP-5 might be a major regulatory factor in the process of hair follicle development of Inner Mongolia Cashmere goat. |
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| Keywords: | Inner Mongolia Cashmere goat IGFBP-3 IGFBP-5 hair follicle cycle |
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