| MicroRNA对皮肤毛囊发育调控的研究进展 |
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| 引用本文： | 张桂山,徐晶,姜怀志.MicroRNA对皮肤毛囊发育调控的研究进展[J].家畜生态学报,2013,34(6):1-4. |
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| 作者姓名： | 张桂山 徐晶 姜怀志 |
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| 作者单位： | 1. 吉林农业大学 动物科学技术学院，吉林 长春 130118；2.吉林农业大学 发展学院，吉林 长春 130600 |
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| 基金项目： | 吉林省科技支撑计划项目（20110237） |
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| 摘 要： | miRNA是一类由19～25个核苷酸组成的内源性非编码单链小分子RNA,通过与靶基因mRNA3’端非编码区配对结合,降解靶mRNA或阻碍其翻译,进而调节靶基因的表达。文章综述了miRNA的生源说及功能、miRNA在皮肤毛囊中的表达检测以及miRNA对皮肤毛囊发育的调控。
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| 关 键 词： | MicroRNA（miRNA） 皮肤毛囊 发育调控 |
Research Progress on MicroRNA Regulation on Skin and Hair Follicle Development |
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| ZHANG Gui-shan,XU Jing,JIANG Huai-zhi.Research Progress on MicroRNA Regulation on Skin and Hair Follicle Development[J].Acta Ecologae Animalis Domastici,2013,34(6):1-4. |
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| Authors: | ZHANG Gui-shan XU Jing JIANG Huai-zhi |
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| Institution: | 1. College of Animal Science and Technology, Jilin Agricultural University, Jilin Changchun 130118;
2. Development College, Jilin Agricultural University, Jilin Changchun 130600) |
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| Abstract: | MiRNAs are a family of endogenous non coding single strand small RNAs (19 25 nt), combining target mRNA through basepair complementarity to degrade mRNA or disrupt translation of mRNA, then modulating gene expression. This review summarized the biogenesis and function of miRNAs, profiling miRNAs Expression in the skin and hair follicle and regulation of miRNAs on skin and hair follicle development. |
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| Keywords: | MicroRNA(miRNA skin and hair follicle regulation of development |
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