Minor pregnanes from Caralluma adscendens var. gracilis and Caralluma pauciflora |
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| Authors: | Reddy Kommidi Devendar Rao Belvotagi Venkatrao Adavi Babu Gummadi Sridhar Kumar Bobbala Ravi Braca Alessandra Vassallo Antonio De Tommasi Nunziatina Rao Ghanakota Venkateshwar Rao Achanta Venkata Narasimha Appa |
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| Institution: | aDepartment of Chemistry, Kakatiya University, Warangal-506009, Andhra Pradesh, India;bUniversity College of Pharmaceutical Sciences, Kakatiya University, Warangal-506009, Andhra Pradesh, India;cDipartimento di Scienze Farmaceutiche, Università di Pisa, via Bonanno 33, 56126 Pisa, Italy;dDipartimento di Scienze Farmaceutiche e Biomediche, Università di Salerno, via Ponte Don Melillo, 84084 Fisciano, Italy |
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| Abstract: | Phytochemical investigation of Caralluma adscendens var. gracilis and Caralluma pauciflora (Asclepiadaceae) whole plant extracts allowed to isolate one pregnane glycoside and two pregnanes characterized as 12β,20-O-dibenzoyl-5α,6-dihydrosarcostin β-oleandropyranosyl-(1→4)-β-cymaropyranosyl-(1→4)-β-digitoxypyranosyl-(1→4)-β-cymaropyranosyl-(1→4)-β-cymaropyranoside (1), 12β-O-benzoyl-3β,11α,14β,20R-pentahydroxy-pregn-5-ene (2), and 11α-O-benzoyl-3β,12β,14β,20R-pentahydroxy-pregn-5-ene (3), respectively. Their structural characterization was obtained on the basis of extensive NMR spectral studies. Three known pregnane glycosides along with lupeol and β-sitosterol were also isolated and characterized. |
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| Keywords: | Caralluma adscendens var gracilis Caralluma pauciflora Asclepiadaceae Pregnanes Spectral analysis |
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